Edman Degradation
The Edman degradation takes advantage of unique nucleophilic reactivity of the N-terminal amino group to determine the sequence of a polypeptide from N-terminus to C-terminus, residue by residue. 00:00 Introduction 00:55 Cleavage and Cyclization by PIC 02:47 Mechanism of Cleavage by PIC 04:54 Summary
The Edman degradation takes advantage of unique nucleophilic reactivity of the N-terminal amino group to determine the sequence of a polypeptide from N-terminus to C-terminus, residue by residue. 00:00 Introduction 00:55 Cleavage and Cyclization by PIC 02:47 Mechanism of Cleavage by PIC 04:54 Summary